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How to Reduce Wrinkles With Retin A. Retin-A is a topical prescription medication made from an acidic form of vitamin A. The generic name is tretinoin or. One Reddit user shared a photo of her year-old grandma's skin after using Retin-A for over 50 years, and she basically has no wrinkles. Have you started to notice wrinkles developing on your face? From crow's feet to frown lines, and forehead wrinkles, facial wrinkles can develop in a variety of.
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